Michael Misfeldt, PhD
Professor, Molecular Microbiology and Immunology
Molecular Microbiology and Immunology
One Hospital Drive, M616
Columbia, MO 65212
573-882-2210
MisfeldtM@missouri.edu
Dr. Misfeldt’s laboratory is examining the expression and function of a family of innate pattern recognition receptors (PRRs), the toll-like receptors (TLRs). Toll-like receptors function in pathogen sensing by recognizing molecular patterns associated with a broad range of pathogens including bacteria, viruses, fungi, and protozoa. TLRs initiate intracellular signaling pathways which culminate in the production of proinflammatory cytokines, chemokines, and antiviral molecules which shape the adaptive immune response.
More information on Dr. Misfeldt and his lab can be found here.
Research Areas of Interest
Cell biology
Confocal fluorescence microscopy
Immunobiology
Immunocytochemistry EM/LM
Immunology
Microarray analysis
Microbiology
Pathobiology
Receptor biology
Rheumatology
Transgenics
